Functionalizable coaxial PLLA/PDLA nanofibers with stereocomplexes at the internal interface

Abstract Multifunctionality of electrospun polylactic acid (PLA) nonwovens was generated by the morphological design nanofibers. Coaxial fibers with a lower number average molar mass M n PLLA core and higher PDLA shell form PDLA–PLLA stereocrystals at interface, induced annealing. In tensile tests under physiological conditions, core–shell crystallinity (22% compared to 11–14%) had Young’s moduli E (9 ± 1 MPa) elongation break ε b (26 3%) than alone ( = 31 9 MPa, 80 5%), which can be attributed simultaneous crystallization relaxation effects. Gelatin incorporated in phase presented on outer surface providing biointerface putatively favorable for cell adherence. incorporation did not influence behavior but slightly lowered T g (60 → 54 °C). Employing exclusively polymers established clinic, multifunctionality design. Graphic abstract